No.
Queen Tiye, wife of Amunophis III, is the mother of Amunophis IV, also known as Akhenaton the Heretic, who was Nefertiti’s husband.
It’s theorized that Ay, Pharaoh after Tutankahmun, may have been Nefertiti’s father, as he uses “Father of the God” as one of his titles. This would be a stretch if Nefertiti was a usual queen, but… She is thought to have been considered equal to her husband in his rule, perhaps named co-regent before Akhenatons death.

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