There were four Macedonian wars between Rome and Macedon, the most powerful state in mainland Greece.
There was the also the Roman-Seleucid war in which Rome and two of her allies (the island of Rhodes and the kingdom of Pergamon in western Turkey) fought the Seleucid kingdom (a kingdom which covered the Middle East and part of Turkey) and its allies in mainland Greece, the Aetolian league (a league of city states in central Greece). Rome repelled a Seleucid attempt to invade Greece.

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