The little Ice Age spanned from 1400 AD – 1800 AD and had an average drop of 2-3 deg C. This caused the crop seasons to become shorter with harsher winters and shorter summers. This was also a contributing factor in the black plague outbreak which accured during this time. 1/3 of the population of Europe was wiped out from the disease which is about 25 million people. So you could argue all that is caused from the little ice age.
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Side note: A real ice age is an average drop of about 7-10 deg and would have much worse effects. Immagine 1/3 of Europe being wiped out today from an ice age. That would be 244 million people. Lack of crops means lack of food for an over populated society, which means a total breakdown of society.